We house state-of-the-art equipment for use in forensic research.
Additional support to faculty is provided by the Advanced Mass Spectrometry Facility and the Department of Chemistry and Biochemistry.
Equipment
- Forensic DNA Profiling Equipment
Instrumentation:
- Stratalinker
- MiSeq FGx Sequencer
- iScan Microarray System
- BioRad T100 thermocycler
- Eppendorf thermomixer
- Eppendorf refrigerated thermomixer
- 3x Eppendorf 5415D benchtop centrifuges
- Eppendorf Vacufuge
- BioRad C1000 thermocycler
- Eppendorf 5804 centrifuge + deep well plate rotor
- 2x Eppendorf 5430 Refrigerated Centrifuges
- 2x High Speed Digital Microplate shakers
- PBI
barocycler - Maxwell 16 automated extraction system
- Freedom EVO-Tecan Robotic Liquid Handler
- ABI 310 Genetic Analyzers
- ThermoFisher ABI SeqStudio Genetic Analyzer
- 2x Hybridization ovens (Illumina Microarrays)
- Vacuum
dessicator - Thermal plate sealer
- Qubit 2.0 Fluorometer
- Qubit 4.0 Fluorometer
- Quant Studio 3 High Resolution Melt PCR System
- ProFlex thermocycler (96-well block)
- Eppendorf D30 Biophotometer
- OMAX digital microscope
- Ohaus analytical scale
- 3x laminar flow hoods
Software:
- Sequencher (one PC license and one Mac license)
- CLC Genomics
workbench (Network license) with Microbial workbench (2 desktop licenses) - Geneious
- BaseSpace (Illumina) Commercial Subscription
- Illumina Experiment Manager/Sequencing Analysis Viewer
- GenomeStudio+Methylation
- ExactID
PrimerE - GeneMapper v3.1
- Trace Evidence Analysis Equipment
- Foster and Freeman Glass Refractive Index Measurement System(GRIM)
- Varian GC/Ion Trap/MS-MS (2 available)
- Several GC/FID (Flame Ionization Detectors)
- Purge and Trap GC/NPD
- HP-6890 GC/MS with headspace, pyrolysis, and liquid sampling options. Negative/Positive mode
- PE SCIEX ELAN DRC II ICP-MS
- LSX 500Plus Laser Ablation (266nm laser for ICP-MS or ICP-OES)
- GC/Atomic Emission Spectroscopy
- HPLC with Electrochemical Detector
- Capillary Electrophoresis
- Finnigan/Thermoquest HPLC-PDA-MS
- Bruker 400 MHz NMR
- FT-IR Spectrometer
- Isco Supercritical Fluid Extractor (SFE)
- Pharmacia FPLC (2 available)
- Several HPLC/UV Detectors
- Detector GE Ion Trak (IMS)
- Hitachi FMBIOII Gel Electrophoresis Analyzer
- PE Applied Biosystems 310 CE Genetic Analyzer
- Several Thermocyclers of various brands
- Intoxilyzer 5000 (CMI)
- Beckman P/ACE CE systems with various detectors
- Beckman MSQ CE system with UV and PDA detectors
- Agilent 7700 ICP-MS with optional hydrogen and/or helium cell gases
- PE Optima 7300 DV ICP-OES
- Thermo Element 2
High Resolution ICP-MS - New Wave UP213 Laser Ablation (213 nm laser for ICP-MS or ICP-OES)
- Applied Spectra J200 Laser Ablation & LIBS (266 nm laser for ICP-MS, ICP-OES, LIBS, or tandem)
- Keyence Digital Microscope (
high resolution 3D imaging and depth profiling) - VSC 2000 Video Spectral Comparator
- Milestone Ethos Up Microwave Digestion
- Environmental Express Hot Block Digestion
- Mill and Pellet Press
- Several types of microscopy equipment including stereo microscopes, PLMs, Phase Contrast Microscopes and several digital interfaces for teaching
- Forensic and Analytical Toxicology Equipment
- Agilent 6530 LC- QTOF-MS/MS mass spectrometer with 1290 Infinity UHPLC, Jet Stream ESI technology, and atmospheric pressure chemical ionization capabilities. General unknown screening and confirmation of licit and illicit drugs and other xenobiotics in seized materials and human specimens; metabolite analysis; analysis of peptides and proteins.
- Agilent 6460 and 6470 LC-QQQ-MS/MS mass spectrometers with 1290 Infinity UHPLC and Jet Stream ESI technology; both instruments equipped for online SPE. Screening, confirmatory, and quantitative analysis of licit and illicit drugs, including novel psychoactive substances (NPS) and other xenobiotics, in seized materials and human specimens for academic and private sector clients.
- Agilent 7890/5975 GC-MS system with 7693 automatic liquid sampler. Split/splitless injection port, electron impact (EI) ionization capability and equipped with 150 sample vial tray. Customized method development for
private sector and academic research laboratories, including forensic and analytical toxicology screening and quantitative analysis. - Agilent 7890 dual-column GC equipped with dual 7683 autosamplers and dual μECDs. Analysis of chlorinated pesticides, PCBs, and other halogenated xenobiotics in human specimens and biota.
- Affiliated instrumentation
Dr. DeCaprio's research group:
- Laminar flow biohazard hood
- Labconco RapidVap N2 sample concentrator
- Paragon kiln for glassware cleaning
- Pierce sample derivatization station
- Beckman TL-100 benchtop ultracentrifuge
- SPE vacuum extraction station
- Eppendorf Speed-Vac centrifuge
- Fisher benchtop UV/visible spectrophotometer
- Tekmar tissue homogenizer
- Bio-Rad electrophoresis equipment (large gels, mini gels, Western blot apparatus, gel dryer)